FOR EXPECTANT PARENTS
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Understanding the results
Negative (normal) test result
The Harmony® Test assesses the risk of trisomies 21, 18 and 13 and, upon request, the risk of numerical changes to the sex chromosomes X and Y. In the event of a negative test result with no pathological ultrasound findings, you can rule out the tested disorders in your unborn child with a high degree of probability.
The exception is trisomy 13, for which latest figures show a detection rate of 85 – 90% of cases by non-invasive tests of maternal blood (NIPT). This chromosomal disorder, however, is very rare, with a frequency of 1:10000 (depending on the mother’s age)1 and can be easily detected by an ultrasound scan, e.g. during first trimester screening.
All NIPT methods have limits when it comes to the detection of mosaics or structural chromosomal changes. The Harmony® Test only investigates the most common chromosomal disorders, so it cannot identify any physical disorders in the child; therefore a negative (normal) test result does not rule out the possibility of other disorders in your unborn child. A number of these disorders can be detected with an accurate ultrasound scan, often from the 12th week of pregnancy. A genetic test such as the Harmony® Test can never replace a thorough ultrasound scan.
If you have any further questions your physician will be pleased to help during your entire pregnancy. You can also contact our team of physicians at any time should you have any questions.
Positive (abnormal) test result
FOR EXPECTANT PARENTS
SEARCH
Understanding the results
Negative (normal) test result
The Harmony® Test assesses the risk of trisomies 21, 18 and 13 and, upon request, the risk of numerical changes to the sex chromosomes X and Y. In the event of a negative test result with no pathological ultrasound findings, you can rule out the tested disorders in your unborn child with a high degree of probability.
The exception is trisomy 13, for which latest figures show a detection rate of 85 – 90% of cases by non-invasive tests of maternal blood (NIPT). This chromosomal disorder, however, is very rare, with a frequency of 1:10000 (depending on the mother’s age)1 and can be easily detected by an ultrasound scan, e.g. during first trimester screening.
All NIPT methods have limits when it comes to the detection of mosaics or structural chromosomal changes. The Harmony® Test only investigates the most common chromosomal disorders, so it cannot identify any physical disorders in the child; therefore a negative (normal) test result does not rule out the possibility of other disorders in your unborn child. A number of these disorders can be detected with an accurate ultrasound scan, often from the 12th week of pregnancy. A genetic test such as the Harmony® Test can never replace a thorough ultrasound scan.
If you have any further questions your physician will be pleased to help during your entire pregnancy. You can also contact our team of physicians at any time should you have any questions.
Positive (abnormal) test result
Understanding the results
Negative (normal) test result
The Harmony® Test assesses the risk of trisomies 21, 18 and 13 and, upon request, the risk of numerical changes to the sex chromosomes X and Y. In the event of a negative test result with no pathological ultrasound findings, you can rule out the tested disorders in your unborn child with a high degree of probability.
The exception is trisomy 13, for which latest figures show a detection rate of 85 – 90% of cases by non-invasive tests of maternal blood (NIPT). This chromosomal disorder, however, is very rare, with a frequency of 1:10000 (depending on the mother’s age)1 and can be easily detected by an ultrasound scan, e.g. during first trimester screening.
All NIPT methods have limits when it comes to the detection of mosaics or structural chromosomal changes. The Harmony® Test only investigates the most common chromosomal disorders, so it cannot identify any physical disorders in the child; therefore a negative (normal) test result does not rule out the possibility of other disorders in your unborn child. A number of these disorders can be detected with an accurate ultrasound scan, often from the 12th week of pregnancy. A genetic test such as the Harmony® Test can never replace a thorough ultrasound scan.
If you have any further questions your physician will be pleased to help during your entire pregnancy. You can also contact our team of physicians at any time should you have any questions.
